CBD (cannabidiol), which was administered to healthy subjects 90 minutes before smoking a marijuana joint, had no effect on the subjects' psychological and heart rate effects.
Researchers from the Department of Psychiatry and the Institute of Psychiatry in New York, Columbia Medical Center and other institutions, published these results in the journal Neuropsychopharmacology. They conducted a double-blind laboratory study in which 31 marijuana smokers were given 0, 200, 400 or 800mg of CBD orally, and marijuana with a THCconcentration of 0.01% (inactive) or about 5.5% (5.3-5.8%) in 8 different trials. Do you like it? Like us
CBD (see → what is CBD), which by itself does not cause any significant psychoactive or circulatory reactions, did not significantly change subjective ratings of "intoxication" or heart rate. Taking cannabis on its own, subjective effects and ratings of cannabis did not differ regardless of CBD dose and placebo capsules.
The authors concluded that their "findings suggest that CBD taken orally does not reduce the reinforcing psychological or positive subjective effects of marijuana smoking."